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4.5 from 102 votes

Southwest Meatloaf

Southwest Meatloaf is a classic meatloaf recipe with a southwestern spin. Crushed tortilla chips and bottled salsa give this easy meatloaf a zesty edge.

Prep Time
15 mins
Cook Time
1 hr 15 mins
Total Time
1 hr 20 mins
Servings: 4
Calories: 679 kcal
Course: Main Course
Cuisine: American

Ingredients

Meatloaf:
  • 2 pounds Certified Angus Beef® brand ground beef
  • 1/2 cup tortilla chip crumbs
  • 1 teaspoon smoked paprika
  • 1 teaspoon ground cumin
  • 1/2 teaspoon garlic powder
  • 1/2 teaspoon white pepper
  • 1/2 teaspoon kosher salt
  • 1 cup salsa
  • 1 1/2 cups pepper jack cheese , shredded
  • 2 large eggs , lightly beaten
  • cooking spray
Meatloaf Glaze:
  • 3 tablespoons ketchup
  • 1 tablespoon lime juice
  • 1 teaspoon onion powder
  • Dash of fine sea salt
Corn Relish:
  • 1 tablespoon butter
  • 2 ears of corn , corn cut off
  • 1/2 white onion , chopped
  • 1/4 teaspoon fine sea salt
  • 1/4 teaspoon smoked paprika

Instructions

    Cup of Yum
  1. Preheat oven to 350 degrees. Spray a meatloaf pan with cooking spray.
  2. In a large mixing bowl, stir together tortilla chip crumbs, smoked paprika, cumin, garlic powder, Kosher salt and white pepper. Add salsa, stir to moisten and allow to sit for 10 minutes.
  3. Add ground beef, breaking apart as you go. Top with beat eggs and shredded pepper jack cheese.
  4. Using clean hands, lightly toss. Do not over mix. Overmixing will result in tough meatloaf.
  5. Gently pack into meatloaf pan. If you don't have a meatloaf pan, you can form it into a rectangle on an aluminum foil lined rimmed baking sheet.
  6. Cover with aluminum foil and bake at 350 degrees for 50 minutes.
  7. Meanwhile, stir together ketchup, lime juice, onion powder and salt. Set aside.
  8. In a medium skillet, heat melt butter over medium heat. Add corn, onion, fine sea salt and smoked paprika. Cook until onions are soft and corn is a bright yellow. Remove and set aside until ready to serve.
  9. Remove meatloaf and brush ketchup mixture over top of meatloaf. Bake for an additional 10-15 minutes uncovered or until a meat thermometer registers at 160 degrees.
  10. Let stand for 5-10 minutes before slicing.
  11. Serve with a serving of corn relish.
  12. If you've tried this recipe, come back and let us know how it was! 

Notes

  • If you're trying to be a bit healthier, you can use ground turkey or ground chicken in your southwest meatloaf instead. These tend to become a bit dry, however, so I still like to use a mixture of ground beef in there.

Nutrition Information

Calories 679kcal (34%) Carbohydrates 28g (9%) Protein 65g (130%) Fat 33g (51%) Saturated Fat 16g (80%) Cholesterol 267mg (89%) Sodium 1499mg (62%) Potassium 1262mg (36%) Fiber 3g (12%) Sugar 9g (18%) Vitamin A 1295IU (26%) Vitamin C 6.9mg (8%) Calcium 401mg (40%) Iron 7.4mg (41%)

Nutrition Facts

Serving: 4Serving

Amount Per Serving

Calories 679

% Daily Value*

Calories 679kcal 34%
Carbohydrates 28g 9%
Protein 65g 130%
Fat 33g 51%
Saturated Fat 16g 80%
Cholesterol 267mg 89%
Sodium 1499mg 62%
Potassium 1262mg 27%
Fiber 3g 12%
Sugar 9g 18%
Vitamin A 1295IU 26%
Vitamin C 6.9mg 8%
Calcium 401mg 40%
Iron 7.4mg 41%

* Percent Daily Values are based on a 2,000 calorie diet.

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