
John Wayne Beef Casserole
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Prep Time
10 mins
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Cook Time
10 mins
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Total Time
45 mins
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Servings
8 - 10 servings
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Calories
756 kcal
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Course
Main Course

John Wayne Beef Casserole
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If you are searching for an easy casserole recipe, you are going to love this John Wayne Casserole. It’s packed full of savory beef and veggies, with a golden brown biscuit crust. It will sure be a new family favorite.
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Ingredients
- 16 ounce can jumbo biscuits
- 2 lbs lean ground beef
- 1 ounce package taco seasoning
- 1 cup water
- 1 cup diced sweet onion
- 1 cup diced green pepper
- 1 cup diced red pepper
- 1-10 ounce can tomatoes with chiles
- 1 cup sour cream
- 1 cup mayonnaise
- 8 ounce package cheddar cheese, divided
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Instructions
- Preheat the oven to 350 degrees and prepare a 9x13 baking dish with a light coating of cooking spray.
- Press the biscuits into the prepared baking dish to cover the bottom and partially up the sides.
- Bake the biscuits in the oven for 10 minutes or until golden brown. Remove from the oven and set aside.
- In a large skillet, cook the ground beef over medium high heat until cooked through. Drain and return to the pan.
- Add the taco seasoning, water, onions, peppers and tomatoes and bring to a simmer. Cook for about 5 minutes or until the peppers and onions are tender and the sauce is nice and thick.
- Distribute the meat mixture over the biscuits.
- In a small bowl, stir together the sour cream, mayonnaise and 1 cup of the shredded cheddar cheese.
- Spread the sour cream mixture over the ground beef and top with remaining shredded cheese.
- Bake in the preheated oven for 20-25 minutes or until the cheese is hot and bubbly.
- Allow to cool for 5-10 minutes before serving.
Notes
- Make it Ahead: This recipe is perfect to make ahead of time. Cook the beef and prepare the casserole. Cover with foil and store in the refrigerator for up to 24 hours before baking. Add a few minutes to the cooking time to ensure it is heated all the way through.
- Don’t Skip the Sides: The biscuits puffs a little too much when they are all on the bottom so make sure that when you add them to the baking dish, push the biscuit dough up the sides as well.
- Cool Completely: Before storing this casserole, allow it to completely cool to room temperature.
- Drain Your Meat: Especially if using beef with more fat in it. This keeps your casserole from being greasy.
Nutrition Information
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Calories
756kcal
(38%)
Carbohydrates
37g
(12%)
Protein
36g
(72%)
Fat
51g
(78%)
Saturated Fat
16g
(80%)
Polyunsaturated Fat
17g
Monounsaturated Fat
15g
Trans Fat
0.4g
Cholesterol
128mg
(43%)
Sodium
1345mg
(56%)
Potassium
762mg
(22%)
Fiber
3g
(12%)
Sugar
7g
(14%)
Vitamin A
1480IU
(30%)
Vitamin C
37mg
(41%)
Calcium
298mg
(30%)
Iron
6mg
(33%)
Nutrition Facts
Serving: 8- 10 servings
Amount Per Serving
Calories 756 kcal
% Daily Value*
Calories | 756kcal | 38% |
Carbohydrates | 37g | 12% |
Protein | 36g | 72% |
Fat | 51g | 78% |
Saturated Fat | 16g | 80% |
Polyunsaturated Fat | 17g | 100% |
Monounsaturated Fat | 15g | 75% |
Trans Fat | 0.4g | 20% |
Cholesterol | 128mg | 43% |
Sodium | 1345mg | 56% |
Potassium | 762mg | 16% |
Fiber | 3g | 12% |
Sugar | 7g | 14% |
Vitamin A | 1480IU | 30% |
Vitamin C | 37mg | 41% |
Calcium | 298mg | 30% |
Iron | 6mg | 33% |
* Percent Daily Values are based on a 2,000 calorie diet.
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